女性急性心肌梗死合并糖尿病患者急诊介入治疗的近期疗效分析

In-hospital effect of primary percutaneous corollary intervention on female acute myocardial infarction with diabetes mellitus

目的探讨女性急性心肌梗死(AMI)合并糖尿病患者介入治疗(PCI)手术效果。方法将2003年10月至2006年9月收治的158例女性AMI患者分为糖尿病组(DM组,67例)和非糖尿病组(ND组,91例),于发病12h内行急诊PCI,比较两组患者的临床和冠状动脉造影特征、PCI成功率及术后并发症发生率。结果①糖尿病组患者血脂异常、未绝经患者、前壁AMI百分比均显著高于ND组(分别为41.8%和25.3%、28.4%和11.0%、68.7%和49.5%,P<0.05)。②糖尿病组患者的梗死相关血管为前降支者显著高于ND组(59.7%和41.6%,P<0.05),糖尿病组3支病变率显著高于ND组(79.1%和45.1%,P<0.01)。③PCI即刻成功率、术中无复流发生率、住院期间PCI术后并发症发生率和病死率两组比较差异均无统计学意义。结论急诊PCI治疗女性AMI合并糖尿病患者可获得良好的近期疗效。

Objective To explore the characters of female diabetic with ST-elevation myocardial infarction （STEMI） undergoing emergency percutaneous coronary intervention （PCI） in clinical presentation, procedural success, and in-hospital outcomes. Methods The cIinical data of 158 female patients with STEMI hospitalized from October 2003 to september 2005,who underwent emergency PC1 within 12 hours after the onset, incIuding 67 cases complicated with diabetes mellitus （Group DM）and 91 cases without diabetes （non-diabetes mellitus group,Group ND）,were analyzed respectively. ResuIts （1） There were significant differences in dislipimia,premenopausal woman, the percentages of anterior wall AMI rate. Group DM were significantly higher than those of Group ND（41.8% vs 25.3%,28.4% vs 11.0%,68.7% vs 49.5%,P〈0.05）. （2） In Group DM, the infarction related artery was left anterior descending branch, which significantly higher than that of the Group ND （59.7% vs 41.6%,P〈0.05）. The rate of triple vesseI disease in Group DM was significantly higher than that of the Group ND （79.1% vs 45.1%,P〈0.01 ）.（3）There were no significant differences in the PCI immediate success rate,intra-operational no-reflow rate, post-PCI complication rate and mortality during hospitalization between the two groups. Conclusion Emergency in-hospital PCI i5 effective on female AMI patients with diabetes mellitus.