抗感冒颗粒的质量标准

Study on Quality Standard for Kangganmao Granules

目的:建立抗感冒颗粒的质量标准。方法:采用TLC法对金银花、连翘、荆芥、板蓝根进行鉴别,用HPLC法测定黄芩苷的含量。结果:薄层色谱斑点清晰,空白对照无干扰;黄芩苷在0.075～0.67μg范围内呈良好的线性关系,r=0.9996,平均回收率为97.3%,RSD=1.1%(n=6)。结论:方法简便,结果准确,可用于该制剂的质量控制。

Objective： To establish the quality standard for Kangganmao granules. Method： Flos lonicerae japonicae, fructus forsythiae,herba schizonepetae and radix isatidis were identified by TLC, and the content of baicalin was determined by HPLC. Result： The TLC spots were quite clear, the blank test showed no interference. The linear range of baicalin was 0. 075 - 0.67 μg, r = 0. 999 6, the average recovery was 97.3%, RSD = 1.1% （n =6）. Conclusion： The method is simple and accurate, it can be used for the quality control of the preparation.