摘要
目的:用高效液相色谱法测定复肾宁片中栀子苷的含量。方法:采用Agilent C_(18)(250 mm×4.6 mm,5μm)色谱柱,以乙腈-水(10:90)为流动相,流速:1.0ml·min^(-1),检测波长为238 nm。结果:栀子苷进样量在0.1446～1.446μg(r= 0.9999)范围内,与峰面积呈良好的线性关系。栀子苷的平均回收率为100.9%,RSD=1.1%(n=6)。结论:本方法简便可靠,专属性强,重现性好,可用于该制剂的质量控制。
Objective： To determine the content of geniposide in Fushenning Tablets by HPLC. Method： The Agilent C18 column （ 250 mm×4.6 mm ,5 μm） was used, the acetonitrile-water（ 10：90 ） as mobile phase, the flow rate was 1.0 ml·min^-1 and the detection wavelength was at 238 nm. Result： The linear range of geniposide was 0. 1446 - 1. 446μg（ r = 0. 999 9 ） the everage recovery was 100.9% RSD 1.1% （n =6）. Conclusion： The method is simple,accurate and sensible,and can be used for quality control of geniposide in Fushenning Tablets.
出处
《中国药师》
CAS
2007年第11期1108-1109,共2页
China Pharmacist
