2002～2006年某院病原菌变迁及耐药性分析

Tendency of Bacteria and Drug Resistance During 2002～2006

目的:分析某院主要病原菌分布和耐药性变迁,指导临床合理使用抗菌药。方法:收集广西医科大学第三附属医院2002～2006年全院临床分离的致病菌3060株,进行细菌鉴定和药敏试验。使用SPSS 10.0统计软件完成数据分析。结果:G^+菌790株,G^-菌2270株,致病菌以大肠埃希菌、凝固酶阴性葡萄球菌、铜绿假单胞菌、克雷伯菌属、肠杆菌属最多见。G^+菌对万古霉素的耐药率均很低,G^-菌对亚胺培南的耐药率较低,不动杆菌、铜绿假单胞菌和肠杆菌属具有多重高耐药性。结论:根据细菌药敏,合理使用抗菌药物控制感染,对降低细菌耐药率有现实意义。

Objective ： To determine the tendency of main bacteria and drug resistance, provide reference for the clinical reasonable application of antibiotics. Method： Bacteria isolated from patients during 2002 - 2006, Total of 3060 Bacterial strain were appraised and analyzed, SPSS10.0 was used to analyze the results. Result： Seven hundred and ninety strains of Gram positive cocci and 2270 stains of Gram negative bacilli. E. coli, Klebsiella, Enterobactor, P. aeruginosa and CNS were the main microorganisms. There Gram-position strains were lower resistance to Vancomycin, The Gram-negitive bacilli were all susceptible to Imipenem, Acineto bacter, Enterobactor and Paeruginosa were multi-drug resistance. Conclusion： Used antibiotics reasonablely by susceptibility test. The resistant rates of bacteria would be decreased.