两组生源大学生入学时的血清抗精子抗体检测

Detection of Sera Antisperm Antibody on Overseas Chinese and Mainland Freshmen

目的:了解外招生源和内地生源的大学生入学体检时的血清抗精子抗体的状况。方法:640名大学新生按生源和性别分为4组:外招生男性组96例(A组),女性组115例(B组);内地生男性组256例(C组),女性组173例(D组)。结合新生入学体检获取血清,应用浅盘精子凝集试验(SAT)、浅盘精子制动试验(SIT)和间接免疫珠试验(iIBT),检测血清抗精子抗体。结果:A、B和D组分别检出SAT抗精子抗体阳性各2例,C组检出4例;这10例iIBT的免疫珠附着率为20%-55%。A-D组的SAT抗体阳性率分别为2.1%,1.7%,1.6%和1.2%。B组检出SIT阳性1例。A组与C组、B组与D组的SAT抗体阳性率比较无显著性差异(P>0.05)。结论:外招生源和内地生源的大学生,入学时可检出血清抗精子抗体,需对大学生开展生殖健康和性健康的教育。

Objective： To investigate sera antisperm antibody for both overseas Chinese and mainland freshmen. Methods： A total of 640 freshmen were divided into 4 groups based on their sources and sex： male overseas Chinese freshmen group （group A, n=96）, female overseas Chinese freshmen group （group B, n=115）, male mainland freshmen group （group C, n=256）, and female mainland freshmen group （group D, n=173）. Their sera were obtained when they underwent physical examination. The tray sperm agglutination test （SAT）, the sperm immobilization test （SIT）, and the indirect immunobead test （iIBT） were used to detect sera antisperm antibodies. Results： In group A, B and D, 2 students with SAT positive were determined, respectively, and 4 cases in group C. The SAT incidence was 2.1%, 1.7%, 1.6%, and 1.2%, respectively. The results of the iIBT on such 10 cases were 20%-55%. One case with SIT positive was found in group B. No significant difference on the incidence was found between A and C groups or B and D groups （P〉0.05）. Conclusion： Antisperm antibody can be detected in both overseas Chinese and mainland freshmen. Freshmen would accept reproductive health and correct sex education.