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转化生长因子β(TGF-β)在肝纤维化中的作用 被引量:6

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作者 殷亮 杨生生
出处 《肝脏》 2007年第5期416-417,共2页 Chinese Hepatology
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参考文献8

  • 1Kunxin Luo.Ski and SnoN:Negative regulators of TGF-b signaling.CurrOpinion Gene Devel,2004,14:65-70.
  • 2Kitamura Y,Ninomiya H.Smad expression of hepatic stellate cells in liver cirrhosis in vivo and hepatic stellate cellline in vitro.Pathol Int,2003,53:1 8-26.
  • 3高春芳.转化生长因子β1与肝纤维化[J].中华医学杂志,2005,85(15):1074-1077. 被引量:23
  • 4Nagashio Y.Inhibition of transforming growth factor beta decreases pancreatic fibrosis an d protects the pancreas against chronic injury in mice.Lab Invest,2004,84:1610-1618.
  • 5Kanamaru Y.Involvement of p3oo in TGF-beta/Smad-pathway--mediated alpha2 (I) collagen expression in mouse mesangial cells.Nephron Exp Nephrol,2003,95:36-42.
  • 6Chadjichristos C,Ghayor C.Down-regulation of human type Ⅱ collagen gene expression by transforming growth factor-beta 1 (TGF-beta 1)in articular chondrocytes involves SP3/SP1 ratio.J Biol Chem,2002,277:43903-43917.
  • 7Philips N.TGF beta-like regulation of matrix metalloproteinases by antitransforming growth factor-beta,and anti-transforming growth factor-beta 1 antibodies in dermal fibroblasts:implications for wound healing.Wound Repair Regen,2004,12:53-59.
  • 8Nakamura T.Inhibition of transforming growth factor beta prevents progression of liver fibrosis and enhances hepatocyte regeneration in dimethyInitresaminetreated rats.Hepatology,2000,32:247-255.

二级参考文献31

  • 1王皓,杨再兴,高春芳,万漠彬,王晓今,Senait Mengsteab,Axel M.Gressner,Ralf Weiskirchen.TGF-β1基因多态性与肝炎后肝纤维化的相关性研究[J].第二军医大学学报,2004,25(12):1284-1287. 被引量:5
  • 2Philips N, Keller T, Gonzalez S. TGF beta-like regulation of matrix metalloproteinases by anti-transforming growth factor-beta, and anti-transforming growth factor-beta 1 antibodies in dermal fibroblasts: implications for wound healing. Wound Repair Regen, 2004,12:53-59.
  • 3Arthur MJ. Fibrogenesis-II. metalloproteinases and their inhibitors in liver fibrosis. Am J Physiol Gastrointest Liver Physiol, 2000,279:245-249.
  • 4Hu MG, Hu GF, Kim Y, et al. Role of p12(CDK2-AP1) in transforming growth factor-beta1-mediated growth suppression. Cancer Res, 2004, 15:490-499.
  • 5de Caestecker M. The transforming growth factor-beta superfamily of receptors. Cytokine Growth Factor Rev, 2004,15:1-11.
  • 6Massague J, Wotton D. Transcriptional control by the TGF β/Smad signaling system. EMBO J, 2000, 19:1745-1754.
  • 7Dooley S, Hamzavi J, Breitkopf K, et al. Smad 7 prevents activation of hepatic stellate cells and liver fibrosis in rats. Gastroenterology, 2003,125:178-191.
  • 8Cutroneo KR, Phan SH. TGF-beta1-induced Smad 3 binding to the Smad 7 gene: knockout of Smad 7 gene transcription by sense phosphorothioate oligos, autoregulation, and effect on TGF-beta1 secretion: bleomycin acts through TGF-beta1. J Cell Biochem, 2003,89:474-483.
  • 9Flisiak R, Pytel-Krolezuk B, Prokopowicz D, et al. Circulating transforming growth factor beta1 as an indicator of hepatic function impairment in liver cirrhosis. Cytokine, 2000,12:677-681.
  • 10George J, Roulot D, Koteliansky VE, et al. In vivo inhibition of rat stellate cell activation by soluble transforming growth factor βtype Ⅱ receptor: a potential new therapy for hepatic fibrosis. Proc Natl Acad Sci U S A, 1999,96;12719-12724.

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二级引证文献59

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