针刺配合耳穴疗法对单纯超重或肥胖症女性血清瘦素及雌二醇的影响

Effect of Acupuncture Combined with Auricular Therapy on Serum Leptin and Estradiol Levels in Female with Simple Overweight or Obesity

目的:观察针刺配合耳穴疗法对单纯超重或肥胖症女性血清瘦素和雌二醇的影响。方法:将60例患者分为2组各30例。治疗组采用针刺配合耳穴疗法治疗。对照组采用行为治疗、饮食治疗、体育锻炼等方法治疗。观察患者治疗前后血清瘦素和雌二醇含量的变化。结果:总有效率治疗组为90.0%,对照组为73.3%,2组比较,差异有显著性意义(P<0.05)。2组治疗前血清瘦素含量升高,与正常对照组比较,差异有非常显著性意义(P<0.01)。2组治疗后血清瘦素含量均下降,与治疗前比较,差异有显著性意义(P<0.05)。2组治疗后血清瘦素含量比较,差异有显著性意义(P<0.05)。治疗组治疗后血清雌二醇含量升高,与治疗前比较,差异有显著性意义(P<0.05)。治疗组降低血清瘦素含量、升高血清雌二醇含量疗效明显优于对照组。结论:针刺配合耳穴疗法可使单纯超重或肥胖症女性血清瘦素含量降低,雌二醇含量升高,起到良性调节内分泌紊乱的作用。

Objective:To observe the effect of acupuncture combined with auricular therapy on serum leptin and estradiol levels in female with simple overweight or obesity. Methods:Sixty patients were equally randomized into 2 groups.Group A received acupunc- ture combined with auricular therapy,group B received behavioral therapy,dietary therapy and exercise therapy.The changes of serum leptin and estradiol levels before and after treat- ment were observed.Results:The total effective rate was 90.0% in group A and 73.3% in group B,the difference being significant between the two groups(P<0.05).Serum lep- tin level was increased in the two groups before treatment as compared with that in the nor- mal group(P<0.01),and decreased after treatment as compared with that before treatment (P<0.05).The serum estradiol level increased in group A after treatment(P<0.05)as compared with that before treatment.The effect on increasing serum estradiol and decreasing serum leptin was better in group A than that in greup B.Conclusion:Acupuncture com- bined with auricular therapy exerts regulatory effect on endocrine disorder by decreasing serum leptin level and increasing estradiol level in female with simple overweight or obesity.