臭氧浓度对经皮椎间盘臭氧溶核术治疗腰椎间盘突出症疗效的影响

Studies on the concentration of oxygen-ozone in percutaneous intradiscal oxygen-ozone-injection for the treatment of lumber disc herniation

目的:探讨臭氧浓度对经皮椎间盘臭氧溶核术治疗腰椎间盘突出症疗效的影响。方法:将收治的264例腰椎间盘突出症患者分为A、B两组,每组各132例,两组患者均在C型臂血管造影机(DSA)透视监测下行经皮椎间盘臭氧溶核术,A组患者椎间盘内注入浓度为40μg/ml的臭氧,B组患者椎间盘内注入浓度为60μg/ml的臭氧,术后1周、1个月、3个月和6个月依据MacNab腰腿痛手术评价标准对两组患者疗效进行评定,计算两组有效率并进行统计学分析。结果:术后1周、1个月时B组患者的有效率分别为95.5%和92.4%,高于A组患者(87.1%和84.1%),两组间比较有显著性差异(P<0.05);术后3个月、6个月时B组患者的有效率分别为83.3%和80.3%,A组患者分别为81.1%和78.8%,两组之间无显著性差异(P>0.05)。结论:臭氧浓度在经皮椎间盘臭氧融核术治疗腰椎间盘突出症中对术后1周、1个月时的疗效有显著性影响,60μg/ml的臭氧疗效较好。

Objectlve：To explore the therapeutic effect of the concentration of oxygen-ozone in the treatment of lumbar disc herniation with percutaneous intradiscal oxygen-ozone-injection.Method：264 cases with lumbar disc herniation were divided into two groups according to the concentration of oxygen-ozone injected into the disc.The concentration of group A was 40μg/ml and the concentration of group B was 60μg/ml.Two groups both accepted the treatment of percutaneous intradiscal ozone-injection under the monitoring with DSA.The therapeutic effect of the treatment were assessed and randomly studied after 1 weeks, 1 month,3 months and 6 months.Result：The result showed that effective rate in group B after 1 week and 1 month was 95.5% and 92.4%,more than the effective rate in group A（87.1% ,84.1%）,with obvious statistic significance（P〈0.05）.The effective rate in group B after 3 month and 6 month was 83.3% and 80.3%,in group A was 81.1% and 78.8%,no obvious difference was observed in the two groups after 3 months and 6 months （P〉0.05）.Conclusion ：The concentration of oxygen-ozone in the treatment of lumbar disc herniation with percutaneous intradiscal ozone-injection has obvious influence on the treatment results after 1 week and 1 month.