脑动脉硬化认知功能与P300的测定

cognition function decline and in patients with cerebral arteriosclerosis the detection of potential P300

目的研究脑动脉硬化患者的认知功能和事件相关电位P300潜伏期的变化特点。方法对60例脑动脉硬化患者进行长谷川量表(HDS)评分和事件相关电位P300潜伏期的测定,结果与同龄正常人作比较。结果脑动脉硬化患者的P300潜伏期比同龄正常人明显延长,认知功能测试得分比同龄正常人低(P<0.001)。结论脑动脉硬化患者有认知功能受损,P300潜伏期延长。

Objective To study cognitive function and changes and features of event-related potential P300 latency in patients with cerebral arteriosclerosis. Methods Hasegawa measuring indicator assign mark and auditory event-related potential were studied separately in 60 patients with cerebral arteriosclerosis, and compare with healthy people of the same age. Results Remarkably lower convulsion scores and delayed latency of event-related potential were found, in patients with cerebral arterioslerosis comyzared with healthy people of the same age （P 〈0. 001 ）. Conclusion Latencies and cognitive desfunetion exists in patients with cerebral arteriosclerosis.