小于胎龄儿发病相关危险因素分析

Analyzing on risk factors related with small for gestational age infant

【目的】分析小于胎龄(small for gestational age,SGA)儿发病的相关危险因素,为临床防治提供参考。【方法】采用1∶2配对的病例对照研究方法,选取本院2005年1月～2006年12月出生的240例单胎活产SGA儿及同期出生的相同胎龄的适于胎龄儿(appropriate for gestational age,AGA)480例,应用Logistic回归分析方法,对其影响因素进行分析。【结果】多元回归分析显示:妊娠高血压综合症、既往异常妊娠史、母亲文化程度低、孕期被动吸烟与SGA发生有关联,其OR值分别为5.65、2.83、3.53、4.71。【结论】妊娠高血压综合症、既往异常妊娠史、母亲文化程度低、孕期被动吸烟,是SGA发生的危险因素,应从孕期保健做起,避免或减少SGA的发生。

[Objective] To analyze the relative risk factors of small for gestational age （SGA） infant. [Methods] The association were examined in a case-control study, in which 240 SGA singleton alive born in our hospital during Jan. 2005 to Dec. 2006, and 480 appropriate-for-gestational-age （AGA） infants matched by infant sex and gestational age were selected. Analyses were performed by logistic regression analysis. [Results] Results from logistic regression showed that oligohydramnors,history of adverse pregnancy outcome, poor maternal education, passive smoking during pregnancy were associated with SGA. The odds ratios of these four factors were 5.85,2.83,3.59,4. 709. [Conclusion] Oligohydr- amnors, history of adverse pregnancy outcome, poor maternal education, passive smoking during pregnancy are risk factors of SGA. More attention should be paid on health protection during pregnancy to avoid or reduce the incident of SGA.