AOPP患者血液流变学和心肌酶含量变化的相关性研究

Study on the Dependablity of Changes of Hemorheology and Myocardial Enzyme in Patients with Acute Organophosphorus Pesticide Poisoning

目的探索急性有机磷农药中毒(Acute Organophosphorus Pesticide Poisoning,AOPP)患者血液流变学变化和心肌酶含量变化的关系。方法对32例重度AOPP患者血液流变学指标(血浆粘度、红细胞聚集指数、红细胞变性能力)和心肌酶含量(CK-MB、LDH)进行连续检测,并对血液流变学指标和心肌酶含量的变化进行相关性分析。结果同健康对照组相比,中毒组患者早期血浆粘度、红细胞聚集指数、CK-MB、LDH均明显升高,红细胞变性能力明显降低(P<0.01):随病情改善血液流变学指标、心肌酶含量呈逐渐恢复趋势。结论AOPP患者心肌酶的变化与血液高粘滞状态有明显的相关性。

Objective To explore the dependablity of changes of hemorheology and myocardial enzyme in patients with acute organophosphorus pesticide poisoning.Methods Monitoring the indicatrixes of hemorheology and myocardial enzyme of 32 cases of AOPP successively and analyzing the dependality of changes of htemorheology and myocardial enzyme.Results Compared with health control group,plasma viscosity,erythrocyte aggregation index,MB isoenzyme of creatine kinase,lactate dehydrogenase of poisoning groups were up,erythrocyte deformability wad down.With the improvement of pathogenetic condition,hemorheology and myocardial enzyme of test group were gradually recovered.Conclusion It is obvious that changes of myocardial enzyme is related to the condition of blood hyperviscous.