子宫非典型性息肉样腺肌瘤1例并文献复习

Atypical Polypoid Adenomyoma of Uterus:1 Case Report and Review of 21 Cases in the Literature

目的探讨子宫非典型性息肉样腺肌瘤(APA)的临床病理学特点,以提高认识,积累诊治经验。方法对苏州大学附一院1例APA及国内已报道APA21例进行总结分析。结果患者多为年轻育龄女性,肿瘤由增生的内膜腺体和平滑肌组成,除1例合并内膜癌患者死亡,其余患者临床经过良好。结论APA主要需与高分化子宫内膜腺癌鉴别,生物学行为介于良性到低度恶性之间,临床处理需结合年龄及生育情况而定,长期随访十分必要。

Purpose To explore the clinical and pathological characteristics in atypical polypoid adenomyomas of the uterus,to improve recognization and accumulate experience of diagnosis and therapy.Method A case report form The First Affiliated Hospital of Soochow University and records of 21 cases gathered by using a literature search were analyzed.Result Patients were almost yong reproductive age women,tumors were composed of hyperplastic endometrium glands admixed with interlacing bundles of muscle cells.One patient was dead because of endometrium caicinoma,others had benign clinical courses.Conclusion Thc major differential diagnosis from atypical molypoid adenomyoma is the well-differentiated adenomyoma carcinoma.It is a benign or a low malignant tumor.Therefore,long-term follow-up is suggested for APA patients.