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代谢综合征与冠状动脉病变程度相关性分析 被引量:1

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摘要 目的:探讨代谢综合征(MS)患者冠状动脉病变程度与MS各指标的关系。方法:选择吉林大学第二医院疑诊冠心病患者共225例,年龄在45-73(52.44±6.82)岁,并行冠状动脉造影检查。确诊冠心病108例,其中合并代谢综合征42例,单纯冠心病66例;非冠心病组117例,其中代谢综合征34例,83例未合并代谢综合征为对照组。标准台式水银血压计测定外周肱动脉收缩压(SBP)和舒张压(DBP),常规方法检测血脂、空腹血糖、血尿酸、餐后2h血糖,进行代谢综合征与冠状动脉病变程度的相关性分析。结果:合并MS的冠心病患者其冠状动脉病变的范围更广,病情更重。Searman相关性分析显示:腹围、BMI、SBP、DBP、LDL-C、HDL-C和餐后2h血糖与冠状动脉病变支数呈明显正相关;Logistic回归分析:冠状动脉病变支数亦与代谢综合征呈明显正相关。结论:合并MS的冠心病患者其冠状动脉病变的范围更广,病情更重。冠状动脉病变支数亦与代谢综合征呈明显正相关。
出处 《吉林医学》 CAS 2007年第13期1447-1448,共2页 Jilin Medical Journal
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  • 1Nesto RW. The relation of insulin resistance syndromes to risk of cardiovascular disease. Rev Cardiovasc Med,2003,4(suppl 6):s11-s18.
  • 2Pouliot MC, Després JP, Lemieux S, et al. Waist circumference and abdominal sagittal diameter: best simple anthropometric indexes of abdominal visceral adipose tissue accumulation and related cardiovascular risk in men and women. Am J Cardiol,1994,73:460-468.
  • 3Brunzell JD, Ayyobi AF. Dyslipidemia in the metabolic syndrome and type 2 diabetes mellitus. Am J Med,2003,115(suppl 8A):24s-28s.
  • 4Robins SJ, Rubins HB, Faas FH, et al. Insulin resistance and cardiovascular events with low HDL cholesterol. The Veterans Affairs HDL Intervention Trial (VA-HIT). Diabetes Care,2003,26:1513-1517.
  • 5Steinmetz A, Fenselau S, Schrezenmeir J. Treatment of dyslipoproteinemia in the metabolic syndrome. Exp Clin Endocrinol Diabetes,2001,109:s548-559.
  • 6Robins SJ, Collins D, Wittes JT, et al. Relation of gemfibrozil treatment and lipid levels with major coronary events: VA-HIT: a randomized controlled trial. JAMA, 2001,285:1585-1591.
  • 7Tan CE, Ma S, Wai D, et al. Can we apply the National Cholesterol Education Program Adult Treatment Panel definition of the metabolic syndrome to Asians? Diabetes Care, 2004,27:1182-1186.
  • 8Lindstrom J, Louheranta A, Mannelin M. The Finnish Diabetes Prevention Study (DPS): Lifestyle intervention and 3-year results on diet and physical activity. Diabetes Care, 2003,26:3230-3236.
  • 9Tuomilehto J, Lindstrm J, Eriksson JG, et al. Prevention of type 2 diabetes mellitus by changes in lifestyle among subjects with impaired glucose tolerance. NEJM, 2001,344:1343-1350.
  • 10Heart Protection Study Collaborative Group, MRC/BHF Heart Protection Study of cholesterol-lowering with simvastatin in 5963 people with diabetes: a randomised placebo-controlled trial. Lancet,2003,361:2005-2016.

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