鸡40Hz听觉相关电位记录方法及反应阈正常值

The 40 Hertz auditory event-related potential in chick:optimized recording conditions and threshold value

为能在同一系统内同时探讨多项测试条件和参数对鸡40Hz听觉相关电位记录结果的影响，采用正交试验法为实验模型，对短音的升／降时间（1、2和3周期）、平台时间（1、2和3周期）、滤波下限（5、20和30HZ）、滤波上限（70、100和250Hz）等四个因素（三个水平）进行筛选，以获得最佳的测试条件。结果发现，短音的升／降时间与平台时间为2－1－2周期，滤波范围为20～70Hz时测试结果最佳。成年鸡各频率反应阈在1．5kHz、2kHz附近最低，且发现6d龄鸡各频率反应阈已达到成年水平，提示其听功能发育已基本成熟。

In order to seek optimized recording parameters for 40 Hz AERP in chick, the pre-sent study was carried out with a statistical model of orthogonal test- The following measuring pa-rameters to be selected includ the rise/decay time of tone pip (1、2 and 3 cycle),platform time (1、2and 3 cycle), high-pass filters (5、20 and 30 Hz), low-pass filter (70、100 and 250 Hz). The re-sults showed that ①the filter setting is a high significant factor, the most optimum basswidth is 20'～70 Hz;②the ideal time of rise/decay and platform of tone pip are 2-1-2 cyCle. The adult animalsshowed the' greatest sensitivity nearby 1. 5~2 kHz frequency. In sixday-old chicks, the thresholdat every frequeny has reached the same values as adult, indicating that their auditory function is es-sentially mature.