谷氨酸柱撑Zn/Al水滑石超分子材料的合成，表征及缓释

SYNTHESIS,CHARACTERIZATION AND RELEASE OF SUPRAMOLECULAR MATERIALS OF GLUTAMIC ACID INTERCALATED Zn/Al LAYERED DOUBLE HYDROXIDES

采用共沉淀法实现了谷氨酸柱撑水滑石层状材料的Zn/Al氢氧化物插层组装,得到结构完整且晶相单一的超分子结构。使用元素分析、X射线粉末衍射、红外光谱及热重-差热分析表征了超分子层状材料的结构。结果表明:谷氨酸成功地插入水滑石层间.得到的材料层状结构完好,层间距从0.86nm增至1.32nm,谷氨酸的分解温度由247～249℃升高到了334℃。此外,结合表征结果建立了谷氨酸柱撑水滑石层状材料的超分子结构模型,并研究了谷氨酸插层水滑石在模拟胃液中的释放性能。

Glutamic acid was intercalated into Zn/Al layered double hydroxides （Zn/Al LDHs） by coprecipitation method. These materials were characterized by X-ray diffraction （XRD）, Fourier transform infrared spectroscopy （FTIR）, thermogravimetric and differential thermal analysis and elemental analysis. A series of absorbed peaks attributed to the stretch of （R-COO-） were observed in the FTIR spectra. The XRD pattern shows that the interlayer space is expanded from 0.86 nm to 1.32 nm. The space expansion indicates that glutamic acid can be intercalated into Zn/Al LDHs successfully. The glutamic acid in the intercalated materials has better thermal stability. The thermal decomposition temperature of the intercalated glutamic acid increases from 247-249 ℃ to 334 ℃. In addition, a model of the supramolecular structure to describe the structure of this material was proposed. The release properties of the LDHs in simulated gastric juice were also studied.