跟骨定量超声和双能X线吸收法测定女性骨密度

Bone minernal density measured by calcaneal quantitative ultrasound measurements and DEXA in female cases

目的:探讨女性跟骨定量超声(QUS)的临床意义及与双能X线吸收法(DEXA)的相关研究。方法:511例20～83岁女性的跟骨定量超声测定﹑骨密度(BMD)测定及研究。结果:女性跟骨超声振幅衰减(BUA)﹑超声传导速度(SOS)和刚度(SI)与腰椎(L2-4),股骨近端(颈部Neck,三角区Ward’s,转子Troch,Total)BMD中度相关(r=0.447～0.625);女性跟骨BUA﹑SOS和SI在50岁以后明显下降;绝经后妇女BUA﹑SOS和SI明显低于未绝经妇女,并随绝经时间延长逐渐下降;骨质疏松症组明显低于对照组。结论:跟骨定量超声能反映健康妇女骨质随年龄的变化,是一种较理想的诊断骨质疏松症的手段,值得推广应用。

Objective：To investigate the clinical significance of calcaneal quantitative ultrasound（QUS） for the female with QUS,and to investigate the relationship of QUS with DEXA. Methods：QUS and DEXA were performed in 511 female cases,aged 20-83 years. Results：Broadband ultrasound attenuation（BUA）,speed of sound（SOS） and stiffness index（SI） of the female calcaneus were moderately related to bone mineral density（BMD） of Lumbar,Femur Neck,Femur Ward＇s,Femur Troch,Total（r = 0.447-0.625）;BUA,SOS and SI decreased obviously when the females were over 50 years old;BUA,SOS and SI in the calcaneus of the postmenopausal women were significantly less than those of the premenopausal women and decreased with the increase of the age. Those parameters of the osteoporosis group were obviously lower than those of the control group. Conclusion：Calcaneal QUS can indicate the change of female bone quality with the increase of ages. This is an effective method to diagnose osteoporosis and worth of introducing widely.