甲氨喋呤肌注治疗异位妊娠的临床分析

Clinical Analysis of Treating Ectopic Pregnancy with Methotrexate Multi-intramuscular Injection

目的探讨甲氨喋呤治疗异位妊娠的疗效。方法回顾分析对81例异位妊娠患者采用MTX保守治疗的情况。结果本组66例成功,成功率81.5%;15例失败,失败率18.5%。治疗成功组与失败组在年龄、孕产次、腹痛发生率、B超提示盆腔包块阳性率等方面无显著差别;在停经天数、接受治疗前的阴道出血时间、血β-HCG值、治疗一周后血β-HCG下降率等方面有显著差别。结论异位妊娠保守治疗成功的关键在于停经及阴道出血时间短,血β-HCG值低。

Objective To probe the curative effect of treating ectopic pregnancy with MTX. Methods With MTX injection, 81 eases of eetopie pregnancy were analysed retrospectively. Results 66 eases turned out to be successful, accounting for 81.5% of the patients, with 15 eases of failure at the failure rate of 18.5%. There were no significant differences between the successful group and the failure group in such aspects as ages, pregnancy time and parity, occurrence rate of bellyache, positive rate of adnexal mass in the pelvic predicted by BUS, but there exist highly significant differences between the two groups in the average menolipsis period, days of vagina bleeding and average β-HCG before the treatment, the declining rate of β-HCG a week after the treatment. Conclusions The key to the success of the MTX treatment is the shorter menolipsis period, fewer days of vagina bleeding and lower β-HCG.