TSGF与CA19-9联合检测对消化道恶性肿瘤的诊断价值

The value of combined detection with TSGF and CA19-9 to the diagnosis of malignant tumors in digestive tract

目的探讨肿瘤相关物质(TSGF)与糖抗原19-9(CA19-9)检测在消化道恶性肿瘤(malignant tumors in digestive tract,MTD)诊断中的价值。方法采用比色法检测TSGF,酶免法检测CA19-9。结果TSGF、CA19-9联合检测MTD的敏感性为89.7%,特异性为92.9%,准确性为92.3%,与单项检测CA19-9相比敏感度明显提高。结论联合检测TSGF、CA19-9能提高MTD的诊断率。

Objective To probe the value of combined detection with tumor supplied group of factors（TS- GF） and carbohydrate 19-9 （CA19-9） to the diagnosis of malignant tumors in digestive tract （MTD）, Methods Serum levels of TSGF and CA19-9 in 116 patients with MTD were determined with spectrophotometry and enzyme immunometric assay（EIA）, respectively, Results In combined detection with TSGF and CA19-9, we can get the diagnostic sensitivity to MTD was 89.7%, specificity was 92.9%, accuracy was 92.3%, accordingly. Contrast with single assay with CA19-9, combined detection has a higher diagnostic sensitivity obviously. Conclusions Detecting TSGF and CA19-9 combinedly can improve the diagnosis rate of MTD.