鸡尾酒疗法治疗57例大面积脑梗死疗效分析

Analysis of therapeutic effect of cocktail therapy on large area of cerebral infarction 57 cases of

目的：探讨鸡尾酒疗法（纳络酮、依达拉奉、三七总皂苷、尼莫地平和甘露醇／甘油果糖）治疗大面积脑梗死的疗效。方法：对57例急性大面积脑梗死患者进行疗效回顾性分析。结果：治愈5例，显著进步9例，不同程度进步26例，总有效率70％；短期内无变化8例，死亡9例（15．8％）。结论：与传统的手术或保守治疗的死亡率（48％-60％）比较，以鸡尾酒疗法治疗大面积脑梗死使死亡率降低。

Objective ：To explore the therapeutic effect of a new cocktail therapy combined with neuroprotectants including naloxone, edaravone, panax notoginsenoside, nimodipine and mannitol or nlycerol-fructose for a large area of cerebral infarction. Method ： 57 cases of large area of cerebral infarction were analyzed retrospectively. Results： 5 cases were cured, 9 cases significantly improved, 26 cases improved at minor extents, 8 cases had no change in a short-term and 9 cases were dead. Conclusion： Compared with surgical or conservative treatment （48% -60% ） , this cocktail therapy can obviously decreased the rates of death and mutilation of a large area of cerebral infarction.