丝裂霉素C联合结膜瓣转位术治疗翼状胬肉的临床研究

The combined use of mitomycin C and conjunctiva -flap transposition operation for the treatment of pterygium

目的丝裂霉素C联合结膜瓣转位术可以降低翼状胬肉的复发率。方法将翼状胬肉患者87例随机分为A、B两组，A组选择传统翼状胬肉切除，B组选择丝裂霉素C联合结膜瓣转位术。翼状胬肉切除后，将0．2mg／ml丝裂霉素C覆盖巩膜创面3～5min，将结膜瓣转位缝合。观察比较两组治疗后复发率。结果A组44例，复发9例，复发率20，45％。B组43例，复发2例，复发率4．88％。B组复发率远低于A组。结论丝裂霉素C联合结膜瓣转位术治疗翼状胬肉是一种简单、安全、有效的方法，值得推广。

Objective To examine whether mitomycin C treatment combined with conjunctival flap switch operation can reduce the recurrence rate of pterygium. Methods 87 cases of pterygium were randomly divided into Group A and Group B. Patients in Group A were treated with tradi- tional pterygium excision, patients in Group B treated with mitomycin C and conjunctiva - flap transposition operation. After pterygium excision the scleral wound was covered with 0.2 mg/ml of mitomycin C for 3 - 5 miniutes and then the conjunctival flap was switched with transposition operation. Results Of 44 cases in Group A, 9 cases relapsed , recurrence rate was 20.45%. Of 43 cases in Group B, 2 cases relapsed, recurrence rate was 4.88%. Recurrence rate in Group B was much lower than that in Group A. Conclusion The combined use of mitomycin C and cenjunctival flap transposition operation is a simple, safe and effective method for the treatment of pterygium.