自然流产妇女与自身抗体之间关系的探讨

To Study the Relatianship between Spontaneous Abortion and Anti-bodyes

目的探讨自然流产与免疫学因素的关系。方法采用酶联免疫吸咐试验（ELISA）对562例自然流产妇女进行血清抗子宫内膜抗体（EMAb）、抗心磷脂抗体（ACA）、抗人绒毛膜促性腺激素抗体（HCGAb）测定。结果562例自然流产妇女中132例HCGAb阳性，阳性率为23．4％；150例EMAb阳性，阳性率为26．7％；184例ACA阳性，阳性率为32．7％；其中63．2％的患者体内有两种以上抗体并存，与对照组比较，有高度显著性差异。结论抗心磷脂抗体、抗人绒毛膜促性腺激素抗体、抗子宫内膜抗体是造成自然流产的不可忽视的免疫学因素。

Objective To immune factor.Methods explore the relationship Anfi-HCG antibody（HCGAb）, anfi-cardiolipm antibody（ACA） of 562 cases of between spontaneous abortion and anfi-endometrial antibody（EMAb）, spontaneous abortion women were determined by using enzyme linked immunosorbent assay（ELISA）.Results Postive rate of HCGAb, EMAb ang ACA was23.4%,26.7%,32.7% and there were two antibodtes about 63. 2% in spontaneous abortion women. Conclusion Anfi-HCG antibodies, anfi-endometrial antibodies and anfi-cardiolipm antibodies were important immune factor of spontaneous abortion.