摘要
研究银杏叶提取物(EGb761)对微血管内皮细胞分泌NO和ET-1的影响。采用体外培养大鼠心肌膜微血管内皮细胞(RMMMVECs)模型,测定其一氧化氮(硝酸还原酶法)和内皮素-1(ELISA法)分泌量的变化。EGb761能显著性提高RMMMVECsNO和ET-1的分泌量,且NO/ET-1值没有显著性变化。
To study the influence of EGb761 on the secretion of NO and ET-1 in microvascular endothelial cells. Using the model of rat myocardium microvascular endothelial cells (RMMMVECs) in vitro, the secretions of NO by the means of nitrate reductase and ET-1 by the means of ELISA were determined. EGb761 could enhance the secretion of NO and ET-1 in RMMMVECs, and the ratio of NO and ET-1 was hardly changed.
出处
《中国农学通报》
CSCD
2007年第11期4-7,共4页
Chinese Agricultural Science Bulletin
基金
北京市自然科学基金A类重点项目(6061001)
北京市教委"学术创新团队"(090245)