脑卒中后抑郁多种相关因素分析

Analysis on multiple correlation factors of post-stroke depression

目的对脑卒中第四周发生脑卒中后抑郁(post stroke depression,PSD)患者进行患病率及多种相关因素的研究,期望对于PSD患者早期诊断和干预治疗提供帮助。方法采用病例-对照研究方案。选用符合标准的所有脑卒中住院患者,抑郁患者为病例组,其余患者为对照组,对各相关因素进行统计学分析。结果共调查101例患者,最后能够配合完成所有调查任务的有88例。PSD总发病人数为33例,占37.5%,其中,轻度抑郁14例,占42.42%,中度抑郁16例,占48.48%,重度抑郁3例,占9.09%。结论神经功能缺损程度为PSD的危险因素,日常生活能力、社会支持为PSD的保护因素。

Objective This research was designed to determine the morbidity and various correlation factors associated with the post-stroke depression （PSD） at week 4 in expection of early diagnosis and intervention for PSD patients. Methods A case-control study program was used. Eligible hospitalized stroke patients were dived into a symptomatic group with depressed patients and a control group with the remaining. All relevant factors were statistically analyzed. Results There were 101 patients surveyed, with 88 patients who completed all the investigations. The overall incidence of PSD was 33 cases, accounting for 37.5%, of which 14 cases were mild depression, accounting for 42.42%; moderate depression 16 cases, accounting for 48.48% and severe depression 3 cases, accounting for 9.09%. Conclusion Neurological impairment counts as a risk factor of PSD, whereas daily living skills and social support are the protective factors.