冠状动脉介入治疗术后严重出血并发症的危险因素分析

Risk factors for major bleeding after percutaneous coronary intervention

目的探讨经皮冠状动脉介入治疗(PCI)术后严重出血并发症的危险因素。方法回顾分析2105例PCI患者中41例严重出血患者(出血组)和随机抽取的50例无严重出血患者(未出血组),使用logistic回归分析与严重出血并发症相关的危险因素。结果与未出血组比较,出血组患者年龄和基础血肌酐水平较高,体重较低。年龄偏大、体重轻和基础血肌酐水平升高是增加PCI术后严重出血风险的独立危险因素。结论年龄、体重和血肌酐水平可以作为预测PCI术后严重出血风险的指标。

Objective To identify risk factors for major bleeding after percutaneous coronary intervention （PCI）. Methods Forty-one patients with major bleeding （group A）and 50 patients without major bleeding（group B） out of 2 105 percutaneous coronary intervention（PCI） patients were analyzed retrospectively. Factors associated with major bleeding were identified using logistic re gression analysis. Results The overall incidence of major bleeding was 1.95% in PCI patients. Patients in group A were older, had lower body weight and higher serum creatinine than those in group B. Advanced age, low body weight, and elevated baseline creatinine were independently associated with a high risk of bleeding （ P 〈0.05）. Conclusion In patients after PCI,major bleeding can be predicted by simple baseline clinical characteristics.