急性白血病患者血清β_2-M测定的临床意义

Clinical significance of serum β_2-M in acute leukemia

目的探讨血清中β2-M的含量与急性白血病的关系。方法采用放射免疫方法检测76例急性白血病患者血清中β2-M,并与50例健康体检人作对照分析。动态观察了19例急性白血病缓解前后血清β2-M水平的变化。结果急性白血病患者的β2-M明显高于正常对照组(P<0.01),而且急性白血病缓解前后血清β2-M水平差异有显著性(P<0.01)。结论血清β2-M可作为急性白血病诊断的一个辅助指标,同时还与白血病预后有一定的关系。

[objective] To explore the relationship between serum β2-M and acute leukemia. [Methods] Radioimmunoassay of serum β2-M in 76 cases of acute leukemia and 50 caes of healthy group were analysized. The difference of serum β2-M before and after remission were observed motively. [Results] Serum β2-M of acute leukemia is higher than that of control group（P 〈0.01）, and the level of serum β2-M before and after remission were significandy different（P 〈0.01）. [Conclusions] Serum β2-M can be used as an index for acute leukemia, and it also has a relationship with prevention.