我院2004-2006年266例药品不良反应报告回顾性分析

ADR Case Reports in Our Hospital During 2004～2006:Retrospective Analysis of 266 Cases

目的：了解我院药品不良反应（ADR）发生的特点。方法：收集我院2004--2006年临床各科室上报的ADR报告266例，并将患者性别、年龄、导致ADR药品种类、临床表现等各项情况输入Excel表进行统计、分析。结果：涉及ADR的药品共86种，其中肝胆用药、抗病毒药引起的ADR较多；静脉途径给药的ADR占56．2％，是引起ADR的主要途径；ADR主要涉及系统为皮肤及附件、中枢神经系统等。结论：临床应重视药品不良反应的报告和监测工作，以减少或避免ADR的发生。

OBJECTIVE： To investigate the characteristics of ADR in our hospital.METHODS： A total of 266 ADR cases reports between 2004 and 2006 in our hospital were collected, which were analyzed statistically by Excel in respect of patients＇ sex, age, drug kinds inducing ADR and clinical manifestations.RESULTS：A total of 86 drug kinds were involved in ADR, with hepatobiliary drugs and antiviral drugs showing the highest percentages; 56.2% were induced by intravenous route.The major systems involved were skin and its appendants, and central nervous system etc.CONCLUSIONS： Great importance should be attached to the monitoring and reporting of ADR in the clinic so as reduce or avoid the occurrence of ADR.