1Polshakov VI, Williams MA, Gargaro AR, et al. High-resolution solution structure of human pNR-2/pS2: a single trefoil motif prorein. J Mol Biol, 1997,267:418-432.
2Wright NA, Poulsom R, Stamp G, et al. Trefoil peptide gene expression in gastrointestinal epithelial cells in inflammatory bowel disease. Gastroenterology, 1993,104: 12-20.
3Newton JL, Allen A, Westley BR, et al. The human trefoil peptide, TFF1, is present in different molecular forms that are intimately associated with mucus in normal stomach. Gut, 2000, 46312-320.
4Longman RJ, Douthwaite J, Sylvester PA, et al. Coordinated localization of mucins and trefoil peptides in the ulcer associated cell lineage and the gastrointestinal mucosa. Gut, 2000, 47: 792-800.
5Lebefvre O, Chenard MP, Masson R, et al. Gastric mucosa abnormalities and tumorigenesis in mice lacking the pS2 trefoil protein. Science, 1996, 274:259-262.
6Calnan DP, Westley BR, May FE, et al. The trefoil peptide TFF1 inhibits the growth of the human gastric adenocarcinoma cell line AGS. J Pathol, 1999, 188:312-317.
8Sonoshita M,Takaku H,Sasaki N,et al.Acceleration of intestinal polyposis through prostaglandin receptor Ep2 in APC716 knockout mice[J]. Nat Med,2001,7(9):1048-1051.
9Stolina M,Sharma S,Lin Y,et al.Specific inhibition of cyclooxygenase -2 restores antitumor reactivity by altering the balance of IL-10 and IL-12 synthesis[J]. J Immunol,2000,164(1):361-370.
10Arvind P,Papavassiliou ED,Tsioulias GT,et al.Prostaglind E2 down-regulates the expression of HLA-DR antigen in human colon adcarcinoma cell lines[J].Biochemistry,1995,34(16):5604-5609.
