摘要
目的：探讨血清同型半胱氨酸在中年人冠状动脉粥样硬化性心脏病，尤其是急性心肌梗死中应用价值。方法：将我院2004年5月～2006年4月心内科住院中年人221人分为三组：1组（急性心肌梗死）；2组（冠状动脉粥样化性心脏病且非急性心肌梗死）；3组（非冠状动脉粥样硬化性心脏病）。用全自动生化仪测定血清同型半胱氨酸水平，并进行统计学分析。结果：三组间两两组间性别、年龄、2型糖尿病及肾功能损伤差异无统计学意义（P〈0．05）。三组间两两组间血清同型半胱氨酸水平几何均数差异有统计学意义（P〈0．05），1组〉2组〉3组。结论：抚顺地区中年人同型半胱氨酸水平增高是很常见的，这可能与地理因素及生活方式有关。血清同型半胱氨酸水平与中年人群冠状动脉粥样硬化性心脏病，尤其是急性心肌梗死密切相关。
Objective：To investigate the application value of serum total homocysteine levels in coronary atherosclerosis heart disease of middle aged persons ,particularly in acute myocardial infarction. Methods-Dividing 221 middle aged persons who were admitted to heart internal medicine department into three groups：l group （acute myocardial infarction） ;2 group （coronary atherosclerosis heart disease and except acute myocardial infarction） ; 3 group （ free of coronary atherosclerosis heart disease ）. Measure serum homocysteine levels and analyse the datas with statistical methods. Results： The difference of sex, age, diabete and impaired renal function between groups showed no statistical significance（P 〉0.05）. Geometric mean serum total homocysteine was the highest in 1 group, higher in 2 group, the difference was statistically significant （P 〈 0.05 ）. Conclusions： The elevation of serum total homocysteine levels of the middle aged persons in Fushun area which could contribute to the expiation of geographical variation and deviation of the lifestyle is very common, the serum total homoeysteine levels is closely related to coronary arterioclerosis heart disease in middle aged persons, particularly to acute myocardial infarction.
出处
《中国民康医学》
2007年第21期937-939,共3页
Medical Journal of Chinese People’s Health
