HA/TCP双相陶瓷的生物矿化研究

Study on the Bio-mineralization of HA/TCP Biophasic Ceramic

采用新型动态体外模拟系统对HA/TCP双相陶瓷进行了体外生物矿化性能研究,通过SEM、EDAX、FT-IR等测试手段研究并分析了模拟体液流速以及钙磷离子补充在矿化过程中对样品表面磷灰石晶体生长影响。研究发现,较低的模拟体液流速下样品表面形成针片状碳酸化羟基磷灰石晶体,而在较高的流速下,晶片交错生长,形成网状结构,将样品表面完全覆盖。同时,模拟体液Ca2+的及时补充也有助于矿化层的形成。

In the present study, a novel mineralization equipment was applied to study the biomineralization property of HA/TCP biophasic ceramic. SEM, EDAX, and FT-IR were used to analyze and evulate the influence of flow rate of SBF and the compensation of Ca^2＋ ion on the formation of apatite layer. The results show that the lamellar crystals were formed on the surfaces of specimen at the lower flow rate, while the surface of specimens was covered by cross-linked lamellar crystals when a higher flow rate was applied. Otherwise, the compensation of Ca^2＋ accelerated the formation of apatite layer.