D-二聚体在泌尿系肿瘤中的应用

Plasma D dimer in urinary tumors

为了解Ｄ二聚体在泌尿系肿瘤患者中的应用价值，采用定量酶联免疫吸附法对４７例泌尿系肿瘤患者及７３例非肿瘤患者血浆Ｄ二聚体含量进行了测定。结果显示：肿瘤患者血浆Ｄ二聚体含量较非肿瘤患者及正常组明显增高（Ｐ＜０．００１），非肿瘤患者与正常组之间无显著性差异（Ｐ＞０．０５）。结果表明，泌尿系肿瘤患者体内处于继发性纤溶活性增高状态，Ｄ二聚体可作为监测泌尿系肿瘤患者的指标之一。

Enzyme linked immunospecific assay to detect plasma D dimer was carried out in 47 urinary tumor patients,in 73 nontumor patients and in normal subjects.D dimer level has been significantly higher in the urinary tumor group than the other 2 groups( P <0.001)while there was no significant difference between the nontumor and the normal group.It was believed that patients with urinary tumors are in a state of secondary fibrinolysis and plasma D dimer might serve as a tumor marker for urinary tumors.