摘要
目的:研究凝血因子Ⅷ活性(Ⅷ:C)、纤维蛋白原(FIB)、D-二聚体(D-D)、凝血因子Ⅴ活性4项血凝指标在妊娠中的变化,探讨其在DIC诊断和预防中的价值。方法:凝血因子Ⅷ活性(Ⅷ:C)、纤维蛋白原含量(FIB)、血浆D-二聚体(D-D)、凝血因子Ⅴ活性测定共3815例(正常非孕妇女314例,正常孕妇3121例,其中DIC患者16例)。结果:DIC和正常孕妇与正常非孕妇女凝血因子Ⅷ活性(Ⅷ:C)、凝血因子Ⅴ差异有统计学意义(P<0.05);FIB、D-D正常孕妇均明显高于正常非孕妇女(P<0.05),并且DIC明显高于正常孕妇(P<0.001)。结论:产前凝血功能检测对预防和治疗DIC的发生和发展有着重要意义。
Objective: To study the level and clinical significance of factor Ⅷ, fibrinogen and D - dimer in pregnancy. Methods: 16 women with DIC, 3 815 normal pregnancy and 314 non - pregnancy women were studied. Results: Factor Ⅷ, fibrinogen and D - dimer activities of women with DIC of pregnancy and normal pregnancy were lower than that of non - pregnancy women ( P 〈 0. 05 ). Fibrinogen and D - dimer with non - pregnancy women were significantly lower than that of DIC of pregnancy and normal pregnancy. Conclusion: Ante natal examination of coagulation function of high value in prevention and treatment of DIC of pregnancy.
出处
《中国妇幼保健》
CAS
北大核心
2007年第31期4383-4384,共2页
Maternal and Child Health Care of China
基金
广东省中山市重点科研项目
广东省卫生科研资助项目