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巴曲酶注射液致血管性水肿

Angioedema induced by batroxobin injection
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摘要 1名66岁男性患者因短暂性脑缺血发作入院治疗。因其血浆纤维蛋白原高,加用巴曲酶10BU静脉滴注。输液1h后患者出现口周麻木、肿胀,10h后呈口周弥漫性肿胀,诊断为血管性水肿,给予西替利嗪治疗5h后,肿胀逐渐消退。次日停用巴曲酶治疗,未再出现血管性水肿。 A 66-year-old man with transient ischemic attack was hospitalized for treatment. Batroxobin 10 BU by intravenous injection was added to his regimen for treating raised plasma fibrinogen. One hour after infusion, he developed perioral numbness and swelling. Ten hours later, he developed perioral diffuse swelling. Angioedema was diagnosed. After 5 hours of cetirizine treatment, his oedema resolved gradually. The next day, batroxobin was withdrawn, and the angioedema did not recur.
作者 孙阳 袁丽萍
出处 《药物不良反应杂志》 2007年第5期377-377,共1页 Adverse Drug Reactions Journal
关键词 巴曲酶注射液 血管性水肿 batroxobin injection angioedema
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