晚期胃癌的手术治疗

Operation for Advanced Gastric Carcinoma

目的:为晚期胃癌的合理治疗提供依据。方法:将1990年至2007年256例IIIb、IV期胃癌患者按其接受不同的手术方式分为姑息性切除组164例和非切除组92例,对比二组间手术效果。结果:姑息切除手术并发症大于非切除组(P<0.05),手术死亡二组差别不大(P>0.05),2年生存率及术后生存质量在姑息切除后能得到明显改善(P<0.05)。结论:姑息切除术效果优于非切除术,晚期胃癌应尽可能争取行姑息切除病灶。

Objective：To provide basis for reasonable treatment for patients with advanced gastric carci- noma. Method： In accordance with different operation 256 patients of TNM stage IIIb and IV gastric carcinoma from 1990 to 2007 were divided into palliative resection group（ n = 164 ） and non-resection group （n = 92 ）. The result of operation were compared between two group. Result： The resection group occurred more postoperative complications than the non - resection group （ P 〈 0.05 ）. No significant difference in operative mortality （ P 〉 0.05 ）. The two - year survival rate and quality of life in resection group was higher than non - resection （P 〈 0.05 ）. Conclusion： The effect of palliative resection is better than that of non - resection. It is preferable that palliative resection be performed for the patients with advanced gastric carcinoma.