NF-κB与脑缺血炎症损伤及中药干预作用

Connection of NF-κB and Cerebral Ischemia Inflammation Injury and Chinese Herb Intervention Effect

脑缺血可诱导NF-κB的激活,NF-κB通过调控多种基因的表达参与了缺血后的炎症反应,在缺血性脑损伤中具有重要作用。针对NF-κB作为治疗脑缺血损伤的靶点对有效防治脑缺血炎症具有重要的理论和临床意义。

NF - kB can be activated by cerebral ischemla and involved in the inflammatory reaction after cerebral is- ehemia by regulating the expression of many kinds of genes, therefore, it plays an important role in ischemic cerebral injury. Aiming at NF - kB as a treatment target of ischemic cerebral injury has an important significance to prevent and cure cerebral ischemia inflammation effectively.