期刊文献+

单核苷酸多态性与冠心病的关联研究

Study about Association of Mononucleotide Polymorphisms with Coronary Heart Disease
下载PDF
导出
摘要 冠心病是由多种危险因素引起的一种复杂的遗传病,近年来,应用单核苷酸多态性研究冠心病的易感因素的遗传基础成为热点,本文就冠心病的易感基因的单核苷酸多态性与冠心病的关系进行综述。 Coronary heart disease is a complicated hereditary disease caused by many risk factors.Recently using mononuleotide polymorphism to study the heredity basis related to predisposing factor of coronary heart disease is becoming hot spot.This article reviews relationship of coronary disease with mononucleotide polymorphism of its predisposing factors.
出处 《医学综述》 2007年第17期1281-1283,共3页 Medical Recapitulate
基金 国家自然科学基金(30060037) 教育部科学技术研究重点项目(03147) 广东省卫生厅科研项目(B2000121)
关键词 单核苷酸多态性 冠心病 基因 Mononucleotide polymorphism Coronary heart disease Gene
  • 相关文献

参考文献20

  • 1Milewiez DM,Seidman CE.Genetics of cardiovascular disease[J].Circulation,2000,102(20 Suppl 4):IV103-IV111.
  • 2Kaessmann H,Zoiiner S,Gustafsson AC,et al.Extensive linkage disequilibrium in a small human populations in Eurasia[J].Am J Hum Cenet,2002,70(3):673-685.
  • 3Volzke H,Robinson DM.Preoperative plasma fibrinogm levels predict mortality after coronary artery bypass grafting[J].Thromb Haemost,2003,89(5):885-891.
  • 4Meade TW,Mellows S,Brozovic M,et al.Haemostatic function and ischaemic heart disease:principal result of the Northwick Park Heart Study[J].Lancet,1986,2(8506):533-537.
  • 5Wilhelmen L,Svardsudd K,Korsan Bengtsen K,et al.Fibrinogen as a risk factor for stroke and myocardial infarction[J].N Ehgl J Med,1984,311(8):501-505.
  • 6Bara L,Nicaud V,Tiret L,et al.Expression of a paternal history of premature myocardial infarction on fibrinogen,factor Ⅶ c and PAL-1 in European offspring:the EARS study[J].Thromb Haemost,1994,71(4):434-440.
  • 7Hamsten A,Iselius L,de Faire U,et al.Genetic and cultural inheritance of plasma fibrinogen concentration[J].Lancet,1987,2(8566):988-991.
  • 8Friedlander Y,Elkana Y,Sinnreich R,et al.Cenetic and environmental sources of fibrinogen variability in Isaeli families the Kibbutzin Family Stydy[J].Am J Hum Genet,1995,56(5):1194-1206.
  • 9Fox CS,Polak JF,Chazaro I,et al.Genetic and environmental contributions atherosclerosis phenotypes in men and women:heritability of carotid intima-media thickness in Genes encoding fibrinogen and cardiovascular risk[J].Hypertension,2001,38(5):199-203.
  • 10van't Hooft FM,von Bahr SJ,Silveira A,et al.Two common functional polymorphisms in the promoter region of the b-fibrinogen gene contribute to regulation of plasma fibrinogen concentration[J].Arterioscler Thromb Vasc Biol,1999,19(6):3063-3070.

共引文献19

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部