运动与冠状动脉粥样硬化性心脏病

Exercise Training and Coronary Heart Disease

内皮功能不全不仅会发生明显的冠状动脉狭窄,而且也被认为是具有危险因素患者的未来心血管事件预测的现象,规律的体育运动作为一种多因素干预的组成部分,显示能对症状的缓解、心肌灌注的增加、降低冠状动脉粥样硬化性心脏病和心肌梗死患者的病死率带来益处,本文旨在阐明运动对生存质量改善所具有的潜在机制,运动介导下减退冠状动脉狭窄、分子水平的内皮功能不全的纠正以及血管再生的重要性是本文讨论的主要关键。

Endothelial dysfunction not only results in significant coronary artery stenosis,but also is considerd as a phenomenon predicting future cardiovascular events of patients with risk factors As.regular physical activity can be considered as a component of multifactorial intervention,it can show the advantages brought to patients in symptom relief,increasion of myocardial reperfusion,decreasion in case fatality of coronary atherosclerotic herat disease and myocardial infarction.This article is to discuss potential mechanism of quality of life brought by move.The importance of exercise training-mediated regression of coronary stenosis,correction of endothelial dysfunction at the molecular level,as well as vasculogenesis are the key of this discussion.