高血糖与重型颅脑损伤患者预后关系的研究

Study on relationship between hyperglycemia and the prognosis in patients with severe craniocerebral injury

目的探讨颅脑损伤患者高血糖与预后的关系。方法将45例颅脑损伤患者按有无糖尿病病史分为2组,检测其损伤后24h内的血糖值,并追踪观察治疗6个月后的预后情况。结果糖尿病组(n=20)与非糖尿病组(n=25)患者损伤后的血糖分别为(11.2±2.5)mmol/L和(9.0±1.7)mmol/L,明显高于正常值(6.1mmol/L),糖尿病组较非糖尿病组患者血糖升高明显(P<0.05),病死率分别为40.0%和28.0%,恢复良好率分别为20.0%和36.0%(P均<0.05)。结论高血糖对颅脑外伤患者的预后有一定的影响,血糖越高,预后越差。

Objective To investigate the relationship between hyperglycemia and the prognosis in patients with severe craniocerebral injury. Methods 45 patients with severe craniocerebral injury were divided into diabetes group（ n =20） and non-diabetes group（ n =25） according to case history.The blood glucose（BG） within 24 h was measured and clinical prognosis was observed after 6-month＇ s treatment. Results The BG in diabetes group and nondiabetes group was （ 11.2 ± 2.5） mmol/L and （9.0 ± 1.7） mmol/L respectively, which were significantly higher than that （6.1 mrnol/L） in healthy persons（ P 〈 0.05）.The mortality in two groups were 40.0% and 28.0% and good recovery rates were 20.0% and 36.0% respectively, there were sign/ficant differences between two groups（ P 〈 0.05）. Conclusion Hyperglycemia may play an important role in the prognosis for the patients with severe craniocerebral injury, and the higher the BG the worse the patients＇ prognosis.