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系统性红斑狼疮活动性与血清骨桥蛋白、白细胞介素10水平的关系 被引量：1

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摘要 [目的]探讨系统性红斑狼疮(SLE)活动性与血清骨桥蛋白、白细胞介素10水平的关系。[方法]SLE患者24例,男性2例,女性22例,诊断均符合1982年美国风湿病学会修订的SLE分类标准。按Bombardier的评分标准,SLE活动指数(SLEDAI)积分>9分为活动期,≤9分为缓解期。将上述SLE患者分为活动期(16例)和缓解期(8例)两组。正常对照组16例,男性4例,女性12例。采用酶联免疫吸附法(ELISA)测定SLE患者和正常对照者血清OPN和IL-10水平。[结果]与正常对照者比较,活动期SLE患者血清OPN和IL-10水平明显升高(P<0.05)。[结论]OPN和IL-10这两种细胞因子可能与SLE的活动性有关。
作者 徐安平 梁艳仪 吕军 王珍 陈学令 李劲高 宛霞
机构地区 中山大学附属第二医院肾内科
出处 《中山大学学报（医学科学版）》 CAS CSCD 北大核心 2007年第B06期44-46,共3页 Journal of Sun Yat-Sen University:Medical Sciences
关键词 系统性红斑狼疮 骨桥蛋白 白细胞介素 活动性
分类号 R593.241 [医药卫生—内科学]
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参考文献21

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二级参考文献8

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共引文献8

同被引文献26

  • 1彭学标.系统性红斑狼疮患者外周血单个核细胞中白细胞介素-10mRNA表达的研究[J].免疫学杂志,2003,19(S1):25-26. 被引量：4
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引证文献1

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中山大学学报（医学科学版）
2007年 第B06期

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