阻塞性睡眠呼吸暂停低通气综合征患者上气道CT测量值与睡眠呼吸暂停低通气指数的相关性

Relationship between upper airway CT measurements and apnea hypopnea indexes of patients with obstructive sleep apnea hypopnea syndrome

目的应用多层螺旋CT对阻塞性睡眠呼吸暂停低通气综合征(OSAHS)患者的上气道成像,探讨上气道各平面的测量参数与睡眠呼吸暂停低通气指数(AHI)的相关性。方法经多导睡眠监测(PSG)确诊的42例OSAHS的患者行平静呼吸和深吸气末时的上气道CT扫描,测量上气道各平面的截面积及相应平面的左右径和前后径并计算气道塌陷度。结果OSAHS患者上气道最小截面积主要位于腭后区;中度组与重度组患者腭后区不同时相各测量指标与AHI呈负相关,舌后区深吸气末各测量指标与AHI呈负相关;各组患者各平面塌陷度与AHI无相关性。结论OSAHS患者气道塌陷度与AHI无明显相关性。

Objective To investigate the relationship between upper airway CT measurements and apnea hypopnea indexes of patients with obstructive sleep apnea hypopnea syndrome （OSAHS）. Methods The pharynxes of 42 patients with OSAHS were scanned by CT during normal respiration and deep inspiration. CT measurements were made in crosssection areas with their corresponding sagittal and transverse diameters, and their pharyngeal collapsibility was also determined. Results （ 1 ） The smallest cross-section area of OSAHS was at the velo-pharyngeal level. （2） At the velo-pharyngeal level CT measurements were negatively correlated with AHI during normal respiration and deep inspiration, and at the tongue-pharyngeal level CT measurements were negatively correlated with AHI during deep inspiration in moderate and serious OSAHS. （3） The collapsibility of different pharynx levels was not correlated with AHI in all cases. Conclusions The collapsibility of different pharynx levels has no correlation with AHI.