移植肾功能延迟恢复八例报告

Delayed Graft Function after Kidney Transplantation(A Report of 8 Cases)

目的：探讨移植肾功能延迟恢复（DGF）的治疗方法。方法：回顾性分析2004年10月-2007年1月8例DGF患者的临床资料。结果：DGF发生率为8.3%（8/96）,其中男6例,女2例;尸体肾移植7例,活体肾移植1例。通过控制液体入量,调整免疫抑制剂,血液透析和并发症的治疗,1例在透析时突发急性左心衰竭抢救无效死亡;7例肾功能恢复正常,恢复时间为11-42 d,患者出院时血肌酐〈150μmol/L。结论：规律性血液透析和免疫抑制剂的调整可以有效地治疗移植肾功能延迟恢复。

Objective： To investigate the clinical treatment of delayed graft function （DGF）after kidney transplantation. Methods：The clinical data of 8 cases DGF performed during October 2004 to January 2007 were retrospectively analyzed. Results：Eight of 96 cases of kidney transplantation occurred DGF,and the incidence rate was 8.3%. In DGF patients, males were 6 cases and female 2 cases. Seven cases occurred in cadaveric kidney transplantation and 1 case in living donor kidney transplantation. Under clinical treatments such as fluid control,immunosuppression adjustment, haemodialysis and complication treatment, 1 case dead during hemodialysis because of acute left ventricular failure,renal function of the rest recovered successfully and recovery time were from 11 days to 42 days. The serum creatinine of all patients declined below 150 μmol/L when discharge. Conclusion.Regular hemodialysis and modulation of immunosuppressants may be an effective treatment on delayed graft function after kidney transplantation.