摘要
Selective adsorption of active ingredients liquiritin and isoliquiritin from Glycyrrhiza uralensis Fisch with multi-walled carbon nanotubes(MWNTs) has been studied.Distribution coefficients of liquiritin between ethanol solvent and r-MWNTs or o-MWNTs in 293K is 37.5 and 43.3,while the distribution coefficients of isoliquiritin between ethanol solvent and r-MWNTs or o-MWNTs is 717 and 1080,respectively.It was indicated that the distribution coefficient of isoliquiritin adsorbed by MWNTs was much larger than that of liquiritin,and oxidation treatment of MWNTs could obviously enhance their adsorption ability.The possible reasons that MWNTs can selectively adsorb isoliquiritin other than liquiritin were discussed on the bases of molecular structure of the active ingredients and their interaction with nanotubes.
Selective adsorption of active ingredients liquiritin and isoliquiritin from Glycyrrhiza uralensis Fisch with multi-walled carbon nanotubes （MWNTs） has been studied. Distribution coefficients of liquiritin between ethanol so/vent and r-MWNTs or o-MWNTs in 293K is 37.5 and 43.3, while the distribution coefficients of isoliquiritin between ethanol solvent and r-MWNTs or o-MWNTs is 717 and 1080, respectively. It was indicated that the distribution coefficient of isoliquiritin adsorbed by MWNTs was much larger than that of liquiritin, and oxidation treatment of MWNTs could obviously enhance their adsorption ability. The possible reasons that MWNTs can selectively adsorb isoliquiritin other than liquiritin were discussed on the bases of molecular structure of the active ingredients and their interaction with nanotubes.
出处
《药学学报》
CAS
CSCD
北大核心
2007年第11期1222-1226,共5页
Acta Pharmaceutica Sinica
基金
国家自然科学基金资助项目(10475109)
国家重点基础研究发展计划资助项目(2006CB705605).
关键词
多壁碳纳米管
甘草苷
异甘草苷
选择性吸附
multi-walled carbon nanotube
liquiritin
isoliquiritin
selective adsorption
