内脏利什曼病、播散型组织胞浆菌病及马内菲青霉菌病的诊断和鉴别

Differential Diagnosis of Visceral Leishmaniasis,Progressive Disseminated Histoplasmosis and Penicilliosis Marneffei

内脏利什曼病(visceral leishmaniasis,VL)、播散型组织胞浆菌病(progressive disseminated histoplasmosis,PDH)和马内菲青霉菌病(penicilliosis marneffei,PMAR)均为人兽共患的感染性疾病,其临床表现以及骨髓或淋巴结等穿刺物涂片镜检的病原体形态相似,故易造成误诊,并常导致严重后果。为此,本文对上述3种疾病的流行病学、临床表现、鉴别诊断及其处理原则等进行简要介绍。

Visceral leishmaniasis, progressive disseminated histoplasmosis and penicilliosis marneffei are infections found in both human and animals. Their clinical manefestations, morphology of the pathogens under microscope are similar. Misdiagnosis was common and prognosis was poor when wrong therapy was given. This article is to introduce the epidemiology, clinical manefestation, laboratory findings and the treatment of these infections.