青海省兴海县国家大骨节病监测点10年监测结果分析

Prevalence analysis of national monitoring outcome in Xinghai Kaschin-Beck disease region from 1997 to 2006

目的掌握青海省大骨节病病情动态变化,为大骨节病防治提供基础资料。方法采用资料回顾性方法,分析1997-2006年国家大骨节病监测点青海省兴海县唐乃亥乡(上、下鹿圈村)7～12岁儿童大骨节病临床检出率和X线检出率。比较2003年与2006年儿童发硒和家中粮食硒水平。结果儿童大骨节病临床检出率在0～20.31%。X线检出率在25.86%～47.97%。2003年儿童发硒为(130.01±48.80)μg/kg,家中粮硒为(41.3±14.9)μg/kg;2006年儿童发硒为(93.71±39.68)μg/kg,家中粮食硒为(8.15±3.44)μg/kg。两年间发硒、粮硒比较差异有统计学意义(t=3.22、10.94,P<0.01)。结论兴海监测点大骨节病病情活跃,病区居民食用自产粮以及粮食收割、储藏、加工不科学与大骨节病关系密切。

Objective To explore the prevalence trend of Kaschin-Beck disease （KBD） to provide basic data for KBD control. Methods Using the method of retrospective analysis, analysis was was performed on clinic prevalence rate and X-ray detectable rate of KBD from 1997 to 2006 among local children aged 7 ~ 12 in Xinghai KBD region. The seneliun content of hair and grain was then compared between 2003 and 2006. Resluts In Xinghai KBD region, prevalence rate above Ⅰ degree, detectable rate of X-ray of children＇s KBD were fluctuated from 0 to 20.31%, and from 25.86% to 47.97%, respectively. Selenium content of hair, grain was （130.01± 48.80） μg/kg and （41.3 ± 14.9）μg/kg in 2003, （93.71 ± 39.68）μg/kg and （8.15 ± 3.44）μg/kg in 2006, respectively, there was a significant difference between 2003 and 2006（t = 3.22,10.94, P 〈 0.01 ）. Conclusions KBD is active in Xinghai region, which is related to the consuming of locally produced grains and unreasonable grain harvesting, persevering and processing.