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致密晶状羟基磷灰石治疗牙周病骨缺损临床疗效观察 被引量:1

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摘要 牙周病造成的齿槽骨破坏吸收,是失牙的主要原因之一,此病引起的骨缺损修复一直是棘手问题,以往采用的植骨方法因有种种缺陷,应用受到限制。近年来,羟基磷灰石作为一种新型骨代用品受到广泛注意。羟基磷灰石Hy—droxyatatito HAP)其化学成份、晶体结构与人体骨骼中的无机物十分相似,经国内外学者临床应用,证明具有良好的生物相容性,无毒,无免疫性,不溶血,不致癌。
作者 满一
出处 《医学理论与实践》 1997年第7期316-317,共2页 The Journal of Medical Theory and Practice
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  • 1张炜真,于世凤,郑麟蕃.白细胞介素1调节成骨细胞分化的实验研究[J].中华口腔医学杂志,1996,31(5):288-291. 被引量:7
  • 2Stenz WC, Brian LM, Pirkka VN et al. Effects of guided bone regeneration around commercially pure titanium and hydroxylapatite-coated dental implants. J periodont, 1997, 68: 199.
  • 3Kobayashi M, Takiguchi R Recombinant human bone morphogenetic protein-2 stimulates osteoblastic differetiation in cells isilated form human periodontal ligment. J Dent Res, 1999, 78 (10) :1621-1633.
  • 4Groenveld EH Burget EH. Bone morphogenetic proteins in human bone regeneration. Eur J Endotrinl, 2000, 142 (1): 9-21.
  • 5Gao TJ, Lindholn Ts, Kommonen B et al. The use of a coral Composite imprant Containing bone morphogenesis protein to repaire a segmental tibial defect in sheep. Iat orthop, 1997, 21(3): 194:200.
  • 6Zellin G, Linde A. lmporfanee of dehrery systems for grollttt stimulatory factors in corbiration coith osteoprometive membranes. An experimenal study using rhBMP-2 in rat mandibular aefccts. J Biomed Mater Res, 1997, 35(2): 181-190.
  • 7Page R. The role of inflammatory mediators in the pathogenesis of periodontal disease. J Periodont Res, 1991, 26:230.
  • 8Jammet P, Souyris F Baldet P. et al, The effect of different porosities in coral implants: An esperimental study. J Craniomaxillofac Surg, 1994, 22: 103.
  • 9Joly JC, Palioto DB, de Lima AF et al. Clinical and radiographic evaluation of periodontal int defects treated with guided tissue regeneration. A pilo study. J Periodonto, 2002,73(4): 353-9 .
  • 10Schantz .JT, Hutmacher DW, Ng KW et al. Evaluation of a tissueengineered membrane-cell constru guided bone regener-ation, int J Oral Maxillofac Implants, 2002,17(2): 161-74.

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