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激素依赖型哮喘患者大剂量皮质激素吸入治疗的临床观察

TREATING STEROIDS DEPENDENT ASTHMATIC PATIENTS WITH HIGHDOSE BECLOMETHASONE DIPROPIONATC ACROSOL
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摘要 大剂量皮质激素加入特非那丁、酮替酚等药物治疗37例激素依赖型哮喘患者,试图撤减口服激素,结果表明:完全撤减成功的占54%,部分撤减的占29.7%,临床症状改善的占13.5%,完全无效的占2.7%,治疗后肺功能较治疗前明显改善(P<0.05)。结果提示大剂量皮质激素吸入是治疗激素依赖型哮喘的较好方法之一。 In order to provide a more effective alternative therapy for the steriod dependent asthmatic (SDA) patients,we studied 37 SDA patients treated with beclomethasone dipropionate(1500μg/d) inhalation instead of oral steroids. The changes of clinical features,pulmonary function were recorded. The results showed that about 83.7% of the patients replaced their oral steroids completely or partially with the inhalation therapy.The clinical features improved in 13 5% of the patients and the faillure rate was only 2 7%.The results also revealed that,after replacement,the pulmonary function of the patients improved ( P <0 05). After alternative therapy for 3-6months,the damaged power and secretive ability of adrenal cortex of the patients were also partially restored( P <0.01).
出处 《锦州医学院学报》 1997年第3期16-18,共3页 Journal of Jinzhou Medical College
关键词 皮质激素 哮喘 剂量 吸入治疗 激素依赖型 asthma adrenal cortex hormones beclomethasone dipropionate
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