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不完全川崎病的临床诊治策略 被引量：11

Clinical Diagnosis and Management of Incomplete Kawasaki Disease
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摘要 不完全川崎病虽不完全符合川崎病的诊断标准,但具有部分川崎病的临床特征。结合临床表现、实验室和超声心动图检查可为不完全川崎病提供诊断线索。治疗主张急性期给予大剂量静脉内丙种球蛋白(IVIG)联合大剂量阿司匹林及恢复期随访;对IVIG不反应者,可应用2剂或3剂IVIG、糖皮质激素及针对细胞因子的单克隆抗体等;已有冠状动脉病变的患儿需长期服用抗凝药物,必要时进行介入或手术治疗。随着对川崎病病因和发病机制以及不完全川崎病的发病率渐增趋势的认识,有必要制定不完全川崎病的诊断和治疗标准。
作者 王凤 桂永浩
机构地区 复旦大学附属儿科医院心血管中心
出处 《国际儿科学杂志》 2007年第6期436-439,共4页 International Journal of Pediatrics
关键词 粘膜皮肤淋巴结综合征 冠状动脉疾病 丙种球蛋白类 阿司匹林 糖皮质激素类
分类号 R725.4 [医药卫生—儿科]
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参考文献23

  • 1Newburger JW, Tskahashi M, Gerber MA, et al. Diagnosis, treatment, and long-term management of Kawasaki disease: a statement for health professionals from the Committee on Rheumatic Fever, Endocarditis, and Kawasaki Disease, Council on Cardiovascular Disease in the Young, American Heart Association[ J ]. Pediatrics,2004,114(6) : 1708-1733.
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  • 3Sonobe T, Aso S, Imada Y, et al. The incidence of coronary artery abnormalities in incomplete Kawasaki disease. Summary and abstracts of the seventh International Kawasaki Disease Symposium: December 4-7, 2001, Hakone, Japan. Abstracts 35[J]. Pediatr Res,2003,53:164.
  • 4王琍,林毅,苏英姿,汪芸,赵地,吴铁吉.283例川崎病的临床分析[J].中华儿科杂志,2004,42(8):609-612. 被引量：84
  • 5Witt MT, Minich LL, Bohnsaek JF, et al. Kawasaki disease: more patients are being diagnosed who do not meet American Heart Association criteria [J]. Pediatrics, 1999, 104( 1 ) : e10.
  • 6Genizi J, Miron D, Spiegel R, et al. Kawasaki disease in very young infants: high prevalence of atypical presentation and coronary arteritis[J]. Clin Pediatr,2003,42(3) :263-267.
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二级参考文献13

  • 1Dajani AS, Taubert KA, Gerber MA, et al. Diagnosis and therapy of Kawasaki disease in children. Circulation, 1993,87:1776-1780.
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共引文献83

同被引文献65

引证文献11

二级引证文献70

国际儿科学杂志
2007年 第6期

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