^(99m)Tc-MIBI显像及CT对原发性甲状旁腺机能亢进症的诊断价值

The value of ^(99m)Tc-MIBI scintigraphy and CT in the diagnosis of primary hyperparathyroidism

目的:评价99mTc-甲氧基异丁基异腈(MIBI)显像及CT在原发性甲状旁腺机能亢进症(PHPT)的临床诊断价值。方法:38例拟诊PHPT患者进行了99mTc-MIBI显像,其中33例同期进行CT检查,并与临床诊断结果进行对比分析和评价。结果:38例中有31例确诊为PHPT,其中甲状旁腺腺瘤29例(包括异位瘤2例),甲状旁腺增生2例,99mTc-MIBI显像诊断敏感性为90.3%,特异性为100%,准确性为92.11%,CT诊断敏感性为57.17%,特异性100%,准确性为63.63%,99mTc-MIBI显像与CT比较差异有显著性意义(P<0.05)。结论:99mTc-MIBI显像作为功能显像在诊断PHPT方面优于CT,是术前定位的重要方法。

ObjeCtive：To evaluate the clinical value of CT and ^99mTc-MIBI scintigraphy in the diagnosis of primary hyperparathyroidism （PHPT） .Methods：38 cases with highly suspected hyperparathyroidism underwent double-phase ^99mTc-MIBI imaging, 33 cases of them underwent CT. Imaging were evaluated according to the final diagnosis and compared with CT. Results： Among 38 cases, 31 hyper- parathyroidism were proven, including 29 cases of adenomas （hyperplasia in 2 cases）. The sensitivity, specifieity and accuracy of ^99mTc-MIBI imaging were 90.3%, 100% ,92.11%. While, the sensitivity, specifisity, accuracy of CT were 57.17%, 100% ,63.63% （ P 〈 0.05）. Condusion：^99mTc-MIBI scintigraphy as functional imaging can diagnose hyperparathyroidism more accurately than CT, and it is an important localizing method for preoperation.