复方苦参注射液对肺癌患者免疫功能的影响

Effect of Composite Radix Sophora Flavescentis Injection on Immunological Function in Patients with Lung Cancer

目的:验证复方苦参注射液的免疫增强作用。方法:将121例肺癌患者随机分为2组,其中治疗组61例,采用基本化疗方案,并在治疗初加用复方苦参注射液20mL静脉滴注,1次.d-1,加用10～14d;对照组60例,仅采用基本化疗方案。2组疗程均为6wk,均在治疗前后进行免疫功能测定。结果:与治疗前比较,治疗组治疗后的免疫功能测定指标有显著增加(P<0.05或P<0.01)。结论:复方苦参注射液能使人体细胞免疫功能增强。

OBJECTIVE： To test and verify the function of Composite Radix Sophora Flavescentis injection in immunologic enhancement. METHODS： A total of 121 patients with lung cancer were randomly assigned to 2 groups： the treatment group （n = 61） received common chemotherapy for 6wk plan in combination with Composite Radix Sophora Flaveseentis injection （20mL,iv gtt） qd for the first 10 to 14 days, while the control group（n = 60） received common chemotherapy alone for 6wk. The indexes of immunity in both groups were detected before and after treatment. RESULTS： The index of immunity in the treat- ment group increased significantly as compared with before treatment（P 〈 0.05 or P 〈 0.01）.CONCLUSION： Composite Radix Sophora Flaveseentis injection can enhance cellular immune function in human body.