摘要
目的探讨体重、体重指数(BMI)等体成分指标对中老年健身运动女性骨密度的影响及体成分指标与骨代谢指标、骨密度指标的关系。方法94例成都市城区健身运动女性根据BMI不同分为三组:低体重组(BMI≤20kg/m2)、正常体重组(20kg/m2<BMI≤25kg/m2))和肥胖组(BMI>25kg/m2),采用Osteospace超声骨密度仪测定跟骨的BUA、SOS、STI骨密度指标;全自动生化分析仪测定血清AKP含量;应用放射免疫法测定血清hCT、BGP、IL-6、E2、TNF含量。应用方差分析和偏相关方法进行统计学处理。结果不同BMI组的体重、体重指数、瘦体重和体脂百分比差异显著,低体重组T-score与正常体重组、超重组比较有极显著差异;低体重组SOS、STI骨密度指标显著低于正常体重组;BUA、SOS、STI骨密度指标与体重、体重指数、瘦体重和体脂百分比呈正相关,与hCT、IL-6、TNF、BGP、AKP呈正相关,与E2呈负相关。低体重组骨量减少、骨质疏松发生率最高。结论体重、体重指数等体成分指标是影响中老年健身运动女性BMD的重要因素,保持体重有利于防止骨丢失和预防骨质疏松发生。
Objective To investigate the effect of body components such as body weight and body mass indexes on the bone mineral density (BMD) of middle and old aged women doing regular physical exercises and the relationships among body component indexes, bone metabolic biochemical indexes and BMD indexes. Methods 94 middle and old aged women doing regular physical exercises were divided into 3 groups (BMI ≤ 20 kg/m^2 , 20 kg/ m2 ≤ BMI ≤25 kg/m^2 , BMI 〉 25 kg/m^2) according to different body mass index (BMI) . BUA, SOS, STI of BMD indexes were tested by Osteospace quantitative ultrasound instruments at calcaneus; The content of serum alkaline phosphatase(AKP) was determined by full-automatic biochemical analysis instrument; The contents of serum calcitonin(hCT), osteocalcin(BGP), interleukin-6( IL-6), estradiol( E2 ) and tumour necrosis factor(TNF) were determined by radioimmunoassay. Statistical analysis was performed by ANOVA and partial correlation between BMI and the parameters was studied. Results There were significant differences of body weight, BMI,lean body mass and body fat percentage among different BMI, and T-score of low BMI group was significantly lower than the normal and overweight groups separately. The SOS and STI of BMD indexes were obviously lower than the normal BMI group. BUA,SOS, STI of BMD indexes were in positive correlation with Body weight, BMI,lean body mass and body fat percentage and positive correlation with the serum contents of hCT, IL-6,TNF, BGP,AKP, but negative correlation to the serum contents of E2 .The prevalences of osteopenia and osteoporosis were low BMI 〉 normal BMI 〉 exceeding BMI. Conclusions The body weight, BMI et al. of body components are important factors that influence human bone health for middle and old aged women doing regular physical exercises, and maintenance of body weight conduces to avoiding bone loss and preventing occurrence of osteoporosis.
出处
《中国骨质疏松杂志》
CAS
CSCD
2007年第11期779-782,共4页
Chinese Journal of Osteoporosis
关键词
骨质疏松
骨密度
体重
体重指数
Osteoporosis
Bone mineral density
Body weight
Body weight index