摘要
目的讨论急性脑卒中患者血清S-100B蛋白的表达规律及临床意义。方法用ELISA法对70例急性脑卒中患者发病24h内的血清S-100B蛋白含量及健康对照组40例进行检测。结果急性脑卒中缺血性和出血性患者血清S-100B蛋白含量均显著高于健康对照组(P<0.01);急性脑卒中缺血性和出血性患者血清S-100B蛋白含量比较,差异无统计学意义(P>0.05);脑卒中含量高低与病情严重程度有密切关系。结论血清S-100B蛋白的含量可作为急性脑卒中病情监测的指标。
Objective To study the expression regularity of serum S-100B and to explore its clinical significance in acute stroke. Methods Enzyme-linked immunosobent assay （ELISA） was applied to measuring the levels of serum S-100B within 24 hours after stroke in 70 patients and 40 normal individuals. Results The serum levels of S100B in patients with cerebral infarction and cerebral haemorrhage were significantly higher than those in normal controls （P〈0.01）. The difference of S-100B level wasn＇t significant between cerebral infarction group and cerebral haemorrhage group. The results revealed the concentration of serum S-100B was closely associated with the degree of stroke. Conclusion The concentration of serum S-100B might be an available index for monitoring the severity of acute cerebral stroke.
出处
《检验医学与临床》
CAS
2007年第10期932-933,共2页
Laboratory Medicine and Clinic
